If genetic data information is involved, data backup shall be carried out for the type of outbound data information, total number of cases, unit / specification, etc., and the data volume of the whole project shall be estimated for data filing. After the filing is approved, data backup shall be carried out regularly. If the actual amount of backed up data is expected to exceed the amount of filed data, filing change shall be carried out; If gene data information is not involved, information backup and filing are not required.