Is An In-vitro Degradation Test Required For Injectable Sodium Hyaluronate Gel For Plastic Surgery? What’s The Specific Requirement?

An in-vitro degradation test is required for injectable sodium hyaluronate gel for plastic surgery. Please refer to YY/T 0962 for the specific requirement, so as to guarantee quality control of the degradation performance of the sodium hyaluronate gel. It is recommended to set multiple time points for observation until the sodium hyaluronate gel is observed to be completely degraded, and upper & lower limits should be developed for the degradation levels at different time points. In the in vitro test, accelerated degradation can be achieved by adjusting test conditions like the concentrations of degrading enzymes.